Prehistoric cultural affiliation(s) include Denali, Akmak, Dry Creek and Eskimo dating back to 12999 BC.
Several famous people are associated with these Yukon-Koyukuk County historic places including Ernest N. Patty and Dr. John W. Chapman.
Some of the country's most noteable architects helped create the Yukon-Koyukuk County places including American Bridge Co., American Car & Foundry Co., Hartley Howard, R. Wood, NPS, Ernest N. Patty, CCC, National Park Service, Alaska Road Commission and Henry Martin. Prominent architectural styles found in Yukon-Koyukuk Country are .