Holmes County Mississippi (Historic Districts) has 4 places on the National Register of Historic Places including 1 place of Statewide significance. Significant places include Holmes County State Park, Holmes County Courthouse Complex, Lexington Historic District, West Historic District.
Some of the country's most noteable architects helped create the Holmes County places including CCC, W. and Company Chamberlain and R. and Company Jesty. Prominent architectural styles found in Holmes Country are Queen Anne, Art Deco and Bungalow/Craftsman.