Knox County Nebraska (Historic Districts) has 3 places on the National Register of Historic Places including 2 places of Statewide significance. Significant places include Ponca Agency Archeological District and Ponca Tribal Self-Help Community Building Historic District, Knox County Courthouse.
Some of the country's most noteable architects helped create the Knox County places including US Government and E.B. Watson. Prominent architectural styles found in Knox Country are Modern Movement.