Prehistoric cultural affiliation(s) include Mississippian and Oneota dating back to 1000.
Several famous people are associated with these La Crosse County historic places including David Franklin Powell and William W. Cargill.
Some of the country's most noteable architects helped create the La Crosse County places including Wenzel Wuensch. Prominent architectural styles found in La Crosse Country are Queen Anne, Italian Villa and Italianate.