De Soto County Louisiana (Vacant / Not In Use) has 5 places on the National Register of Historic Places including 1 place of Statewide significance. Significant places include Keachi Store, Guy House, Longstreet Rosenwald School, Mundy-McFarland House and Scott, Thomas, House.
Some of the country's most noteable architects helped create the De Soto County places including Samuel Eldridge Guy, John W. Mundy and Thomas Scott. Prominent architectural styles found in De Soto Country are Greek Revival and Italianate.