Orangeburg County South Carolina (Historic Districts) has 9 places on the National Register of Historic Places including 4 places of Statewide significance. Significant places include Cattle Creek Campground, Claflin College Historic District, East Russell Street Area Historic District and South Carolina State College Historic District and Amelia Street Historic District.
Some of the country's most noteable architects helped create the Orangeburg County places including Miller F. Whittaker, James B. Urquhart and Lupo & Holcombe. Prominent architectural styles found in Orangeburg Country are Colonial Revival, International Style and Queen Anne.