Yankton County South Dakota (Historic Districts) has 6 places on the National Register of Historic Places including 1 place of National significance and 3 places of Statewide significance. Significant places include Yankton Historic Commercial District, Human Services Center, Yankton College Historic District and Yankton Historic District and Yankton High School Historic District.
Some of the country's most noteable architects helped create the Yankton County places including J.H. Coxhead, Dr. Leonard C. Mead and George Elmslie. Prominent architectural styles found in Yankton Country are Italianate, Prairie School and Romanesque.