La Plata County Colorado (Historic Districts) has 6 places on the National Register of Historic Places including 2 places of National significance. Significant places include Durango-Silverton Narrow-Gauge Railroad and Ute Mountain Ute Mancos Canyon Historic District, East Third Avenue Historic Residential District, La Plata County Fairgrounds and Main Avenue Historic District.
Prehistoric cultural affiliation(s) include Anasazi, Athabascan and Ute dating back to 499 BC.
Some of the country's most noteable architects helped create the La Plata County places including Gen. William J. Palmer, Dan Cummins and Works Progress Administration. Prominent architectural styles found in La Plata Country are Late 19th And 20th Century Revivals and Late Victorian.