Prehistoric cultural affiliation(s) include Shoshone, Owens Valley Paiute, Early Archaic, Late Archaic, Middle Archaic, Silver Lake, Lake Mojave, Pinto Or Little Lake, Eastern Mono and Northern Paiute dating back to 10999 BC.
The famous person Marta Becket is associated with one of more of the Inyo County historic places.
Some of the country's most noteable architects helped create the Inyo County places including Alexander H. McCulloch. Prominent architectural styles found in Inyo Country are Mission/Spanish Revival and Modern Movement.