Prehistoric cultural affiliation(s) include Calusa, Glades Iii, Archaic Stage, Caloosahatchee Sequence, Spanish, Caloosahatchee Culture and Caloosahatchee I-V dating back to 2999 BC.
Many famous people are associated with these Lee County historic places including Henry Ford Sr., Cyrus Teed, Heitman, Gilmer, Sr., William H. Towles, Thomas Alva Edison and John & Frederick Menge.
Some of the country's most noteable architects helped create the Lee County places including Punta Gorda Fish Co., J.T. Rose, N. Gaillard Walker, W.O. Sparklin, Manuel Gonzalez, Henry Van Ryn, Francis J. Kennard, Francis Kennard, G. T. Barker and Phillip Nye. Prominent architectural styles found in Lee Country are Mission/Spanish Revival, Late 19th And 20th Century Revivals and Classical Revival.