Macoupin County Illinois has 8 places on the National Register of Historic Places including 4 places of Statewide significance. Significant places include Carlinville Chapter House, Carlinville Historic District, Route 66, Girard to Nilwood and Union Miners Cemetery and Anderson, John C., House.
Some of the country's most noteable architects helped create the Macoupin County places including Hirsch and Watson Helfensteller, Henry Soulsby and Charles Crossland Robinson. Prominent architectural styles found in Macoupin Country are Italianate, Federal and Greek Revival.