McDonough County Illinois has 8 places on the National Register of Historic Places including 2 places of Statewide significance. Significant places include Kleinkopf, Clarence, Round Barn and McDonough County Courthouse, King, Moses, Brick and Tile Works, Welling-Everly Horse Barn and Western Illinois State Normal School Building.
Some of the country's most noteable architects helped create the McDonough County places including Dick Carmack, Elijah E. Myers, Tri-City Construction Co., Robert Bruce Wilson, Newt Willis and Moses King. Prominent architectural styles found in McDonough Country are Classical Revival, Late Victorian and Stick/Eastlake.