Pulaski County Illinois has 4 places on the National Register of Historic Places including 2 places of National significance. Significant places include Mound City Civil War Naval Hospital and Mound City National Cemetery, Illinois Central Railroad Depot, Olmstead Depot.
Some of the country's most noteable architects helped create the Pulaski County places including Montgomery C. Meigs and Illinois Central Railroad. Prominent architectural styles found in Pulaski Country are Stick/Eastlake and Queen Anne.