Prehistoric cultural affiliation(s) include Middle Woodland, Tchula, Mississippian, Et Al., Poverty Point, Baytown, Wheeler and Marksville dating back to 2499 BC.
The famous person Hugh Jackson Jennings is associated with one of more of the Tallahatchie County historic places.
Some of the country's most noteable architects helped create the Tallahatchie County places including F.B. Construction Co. Hull, W.S. Hull, American Bridge Co. of New York and Frank R. McGeoy. Prominent architectural styles found in Tallahatchie Country are Colonial Revival, Queen Anne and Romanesque.