Prehistoric cultural affiliation(s) include Caddoan and Native American dating back to 500.
Some of the country's most noteable architects helped create the Cherokee County places including Dietrich A.W. Rulfs, W.W. Looney, Edgar Aber, P.A. Sanford, Fred Haberle and James A. Wetmore. Prominent architectural styles found in Cherokee Country are Queen Anne, Classical Revival and Shingle Style.