La Salle County Texas has 4 places on the National Register of Historic Places including 1 place of National significance. Significant places include Welhausen School and Florita Plaza, Cotulla Ranch, La Salle County Courthouse, Welhausen School and Florita Plaza.
Some of the country's most noteable architects helped create the La Salle County places including Henry T. Phelps. Prominent architectural styles found in La Salle Country are Gothic, Mission/Spanish Revival and Moderne.