Greene County Ohio (Historic Districts) has 8 places on the National Register of Historic Places including 1 place of Statewide significance. Significant places include East Second Street District, Dean Family Farm Historic District (Boundary Increase), East Second Street District(Boundary Increase), Grinnell Mill Historic District and Main Street Historic District.
Several famous people are associated with these Greene County historic places including Coates Kinney and Moses Walton.
Some of the country's most noteable architects helped create the Greene County places including Hiram Brown and George Barrett. Prominent architectural styles found in Greene Country are Federal, Greek Revival and Italianate.