Clark County Indiana (Historic Districts) has 10 places on the National Register of Historic Places including 1 place of National significance and 3 places of Statewide significance. Significant places include Indiana State Prison South-Indiana Reformatory- Colgate-Palmolive Historic District, Indiana State Prison South-Indiana Reformatory- Colgate-Palmolive Historic District, Old Jeffersonville Historic District and Pleasant Ridge Historic District and Centralia Court Historic District.
Some of the country's most noteable architects helped create the Clark County places including John Elder, Arthur et al. Loomis, Clarke and Loomis, Gunnison, Foster, Senior, Arthur Loomis, National Homes and John Work. Prominent architectural styles found in Clark Country are Bungalow/Craftsman, Federal and Gothic Revival.