Prehistoric cultural affiliation(s) include Wythe and Radford dating back to 1000.
Several famous people are associated with these Smyth County historic places including Francis Preston, Gen. William Campbell and Hezekiah Love Bonham.
Some of the country's most noteable architects helped create the Smyth County places including R.L. Poor, Henry Carl Messerschmidt, E.L. Myers, Francis Irby, MacDonald Bros., Lewman & Sweeney, Abijah Thomas, R. E. L. Smith, Jesse Dungan and Eubank & Caldwell. Prominent architectural styles found in Smyth Country are Queen Anne, Beaux Arts and Classical Revival.